Spitz melanoma is a distinct subset of spitzoid melanoma
نویسندگان
چکیده
منابع مشابه
Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update
The clinicopathologic classification, diagnosis, and management of Spitzoid melanocytic lesions is one of the most problematic topics in dermato-oncology and dermatopathology. After earlier anecdotal reports [1,2], the controversial history of these controversial lesions began in 1948 when Sophie Spitz described 13 cases of what she called “juvenile melanoma,” underlining its presumably good pr...
متن کاملAre all melanomas the same? Spitzoid melanoma is a distinct subtype of melanoma.
BACKGROUND Although the majority of melanomas demonstrate high rates of mutations in B-RAF or N-RAS that result in constitutive activation of the mitogen-activated protein kinase-signaling pathway, emerging data suggest molecular differences among melanoma subtypes. In this study, the authors evaluated the contribution of B-RAF and N-RAS mutations to the pathogenesis of Spitzoid melanomas. ME...
متن کاملSpitzoid melanoma.
Because spitzoid melanoma shares many histopathologic features with Spitz nevus, it is one of the most difficult lesions to diagnose in dermatopathology. Uncertainty exists in the medical literature about how to diagnose melanocytic proliferations including Spitz nevus and spitzoid melanoma. A misdiagnosis of a melanoma as Spitz nevus is one of the most frequent causes of malpractice lawsuits i...
متن کاملA Case of Spitzoid Melanoma
Spitzoid melanoma is a subtype of melanoma that, clinically and histologically, resembles a Spitz nevus. Clinically, spitzoid melanomas usually evolve from amelanotic nodular lesions, growing to 1 cm or more in diameter. They often remain clinically undiagnosed because of their wide variety of clinical appearances and a lack of pigmentation. Distinguishing a Spitz nevus from a spitzoid melanoma...
متن کاملSpitzoid melanoma: dermoscopic report and diagnostic discussion.
We present a case of a 16-year-old young man who came for a dermatologic appointment due to acne. He presented a pigmented asymptomatic lesion on the back of his right thigh. Dermoscopic examination revealed uncommon aspects, highly suspect of nodular melanoma, in particular a blue-whitish veil, striae and asymmetric globules. The lesion was promptly removed and the material referred for histop...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2020
ISSN: 0893-3952,1530-0285
DOI: 10.1038/s41379-019-0445-z